Study profile of drugresistant tuberculosis at a Northern India hospital

Dr. Urvinderpal Singh; Dr. Bharat Bhushan; Dr. Daksh Jhim; Dr. Kulbir Singh; Dr. Deepak Goyal; Dr. Naresh Kumar; Dr. Anand Kumar Bansal

Volume : V, Issue : X, October - 2016

Study profile of drugresistant tuberculosis at a Northern India hospital

Dr. Urvinderpal Singh, Dr. Bharat Bhushan, Dr. Daksh Jhim, Dr. Kulbir Singh, Dr. Deepak Goyal, Dr. Naresh Kumar, Dr. Anand Kumar Bansal

Abstract :

Objectives: The present study was aimed to elucidate the various aspects of the (M)DR–TB, so as to further improve and strengthen the programme. Materials and methods: Out of the registered 162 patients, 132 qualified for the study during the calendar year of 2012 and standardized treatment regimen (Category IV) was initiated according to RNTCP of India, based on WHO guidelines. Results: The sputum smear conversion and culture conversion rates at 3 months and 6 months were found to be 89.39% and 90.15% respectively. Success rate was found to be 50.75% (cure rate and treatment completion rate combined) and a default rate of 27.27%, with ADRs noticed in majority of patients at different occasions. Discussion and conclusions: Diagnosis of the co–morbidities and recognition of various addictions require timely interventions. Early detection of ADR(s) with appropriate management, responsible DOT provider services, effective monitoring and supervision are the corner stones for desired goal.