Supplementation of Vitamin E on urinary risk factors and Calcium Oxalate Monohydrate binding proteins in urolithiasis

Dr.C.Padmavathi; Dr.G.Brindha

Volume : V, Issue : IV, April - 2016

Supplementation of Vitamin E on urinary risk factors and Calcium Oxalate Monohydrate binding proteins in urolithiasis

Dr. C. Padmavathi, Dr. G. Brindha

Abstract :

The efficacy of supplementation of vitamin E in preventing stone formation was assessed in stone formers. The excretion of total COM binding proteins was elevated in stone formers when compared with that of healthy individuals and normalized in vitamin E treated patients. Apart from these factors, the macromolecules present in the urine are capable of altering the crystallization rate. Hence, the Calcium oxalate monohydrate binding proteins were isolated from these patients yielded three protein peaks and they were designated as fractions I, II and III according to their order of elution. Among the three COM binding protein fractions, the proportion of F I and F III was increased and F II was reduced in stone formers. Identical distribution pattern of COM binding proteins with those of healthy individuals were observed for vitamin E treated patients after 9 months.