SYNCHRONOUS MAXILLO-MANDIBULAR SECOND PRIMARY TUMORS IN A PATIENT TREATED FOR CARCINOMA CERVIX - ROLE OF FIELD CANCERIZATION

Varsha Haridas Upadya; Rohan Shetty; Julie Jacob; Syed Mohammed Miqdad; Saini Mondal

Volume : VII, Issue : IV, April - 2018

SYNCHRONOUS MAXILLO-MANDIBULAR SECOND PRIMARY TUMORS IN A PATIENT TREATED FOR CARCINOMA CERVIX - ROLE OF FIELD CANCERIZATION

Varsha Haridas Upadya, Rohan Shetty, Julie Jacob, Syed Mohammed Miqdad, Saini Mondal

Abstract :

There has been no significant improvement in the long term survival of patients with head and neck cancer in the past few decades despite advances in therapy.An important reason for this is the development of second primary tumors (SPTs) [1]. Apart from loco–regional failure and distant metastasis, SPTs are the major cause of death in patients with head and neck squamous cell carcinoma (HNSCC).Apart from the classic tobacco/alcohol–associated HNSCC, the human papillomavirus (HPV) has emerged as a distinct risk factor for oropharyngeal SCC in recent times, suggesting that there may be distinct patterns of synchronous SPTs [2]. We present a rare case of oral SCC involving extraction sockets of both maxilla and mandible, occurring as synchronous SPTs in apatient treated for SCC of the cervix. The mandibular lesion was initially misdiagnosed as an unhealed socket. The paper highlights the importance of early screening for SPTs during the time of diagnosis of the index cancer as these lesions are more aggressive & metastasize early.