Volume : V, Issue : V, May - 2016

Synthesis, Characterization and Biological Activity of some new Biginelli Products

Mrs. Hina Sattar

Abstract :

 Dihydropyrimidines (DHPMs) are important due to their excellent pharmacological properties. In the present work, we have synthesized new functionalized DHPMs which includes a three component cyclocondensation reaction of benzoylacetone, benzaldehyde and urea, using catalytic amount of concentrated HCl in ethanol. Structures of the compounds have been confirmed by spectroscopic methods. The newly synthesized DHPMs showed prominent anti–microbial activity against the gramnegative (Escherichia coli and Klebsiell ) and gram–positive bacteria (Staphylococcus aureus)

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Mrs. Hina Sattar Synthesis, Characterization and Biological Activity of some new Biginelli Products International Journal of Scientific Research, Vol : 5, Issue : 5 MAY 2016

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