Volume : III, Issue : X, October - 2014

Synthesis, Characterization, Docking Studies And Bio–Efficacy Evaluation of Novel 1,4–Dihydropyridine Derivatives

Mohammed Hadi Ali Al Jumaili

Abstract :

In the present study two new series of Hantzsch 1,4–dihydropyridine derivatives (1,4–DHPs) containing substituted pyrazole moiety (5a and 5c ) were synthesized by the reaction of pyrazole aldehyde with 1,3–dicarbonylcompounds (ethylacetoacetate and methylacetoacetate) and ammonium acetate. The newly synthesized compounds were characterized by IR, NMR, study and also by C, H, N analyses. New compounds were screened for their antimicrobial activity by paper disc method.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Mohammed Hadi Ali AL-Jumaili Synthesis, Characterization, Docking Studies And Bio-Efficacy Evaluation of Novel 1,4-Dihydropyridine Derivatives International Journal of Scientific Research, Vol : 3, Issue : 10 October 2014

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