Volume : III, Issue : VI, June - 2014

Synthesis of some Novel Heterocyclic Compound and their Antimicrobial Activity

Hiral S. Tailor

Abstract :

The quinazolone nucleus is embedded in a large number of alkaloids, drugs, antibiotics, agrochemicals, and antimicrobial agents. Many simple fused quinazolones are biologically active themselves or are essential component of very important naturally occurring substances (i.e. nucleic acids). The reaction of 6-Bromo -2-phenyl-4-H-3,1-benzoxazin4-one(II) with p-amino acetophenone in presence of pyridine gives the resulting compound (III) and this compound when treated with different substituted aldehyde gives the new 6-Bromo-2-phenyl-3-[4-(3-substitutedphenyl-acryloyl)-phenyl]-3H-quinazolin-4-one. (IV). All the compounds have characterized by IR & NMR spectra and elemental analysis.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Hiral S. Tailor Synthesis of some Novel Heterocyclic Compound and their Antimicrobial Activity International Journal of Scientific Research, Vol.III, Issue.VI June 2014

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