IJSR - International Journal of Scientific Research

Kanchan Thakare; Anand Aswar

Volume : VIII, Issue : VIII, August - 2019

Synthesis, structural characterization and antimicrobial activity of transition metal complexes with tridentate hydrazone schiffs base ligand

Kanchan Thakare, Anand Aswar

Abstract :

The transition metal complexes of Ti(III), Cr(III), Fe(III), VO (IV ), MoO2 (VI), WO2(VI), Th(IV) have been synthesized with tridentate N‘–(1–(2,4–dihydroxyphenyl)ethylidene)pyrazine–2–carbohydrazide ligand synthesized from condensation pyrazine– 2– carbohydrazide and 2,4 dihydroxyacetophenone. The synthesized and purified metal complexes were characterized by IR, 1H–NMR, UV– diffuse reflectance, Mass spectra, XRD, TGA, SEM–EDS analysis, magnetic moment. The IR spectral data suggest that the ligand behaves as tridentate moiety with ONO donor atoms sequence towards central metal ion. Free ligand as well as its all metal complexes has been screened against the growth of pathogenic bacteria. The inhibition data revealed that metal complexes exhibit higher inhibition potential against growth of bacteria and fungi than free ligand.