The association of microalbuminuria with components of metabolic syndrome, in North Indian population: A hospital based study

Anju Mittal; Nirensingh Koch; Gautam Sarkar; Akash Gupta

Volume : V, Issue : VII, July - 2016

The association of microalbuminuria with components of metabolic syndrome, in North Indian population: A hospital based study

Anju Mittal, Nirensingh Koch, Gautam Sarkar, Akash Gupta

Abstract :

Introduction – Metabolic syndrome (MetS) is a major public–health problem worldwide. The aim of the study was to explore the association of microalbuminuria and metabolic syndrome. Material & method: The present study was conducted at Department of Biochemistry, Subharti Medical College & Hospital. Metabolic syndrome was diagnosed by the IDF 2005 criteria. A total of 88 consecutive cases of metabolic syndrome were selected for the study. A corresponding number of age & sex matched volunteers were selected as controls. Other than the routine parameters & those pertaining to the diagnosis of metabolic syndrome, microalbumin & creatinine were estimated in all urine samples. Microalbuminuria was defined as urine albumin– creatinine ratio of 30 to 300mg/g. Results: Urinary albumin creatinine ratio (UACR) was significantly higher in cases as compared to control (p<0.002). We observed that 22.7% of case subjects had microalbuminuria, whereas 4.5% of control subjects had microalbuminuria. All components of metabolic syndrome were associated with increased risk of microalbuminuria, the strongest association being with high blood pressure. Conclusion: Microalbuminuria being an independent predictor for cardio–vascular and renal injury, routine screening for microalbuminuria, as additional criteria for metabolic syndrome, should be considered, to further fine tune the interpretation of metabolic syndrome.