Volume : III, Issue : VII, July - 2014

The Prevalence of Antituberculosis Multidrug Resistance in Yemen 2013

Doa A Anwar Ibrahim, Al Akhali A, Farouk A. Al Qadasi

Abstract :

Tuberculosis is an infectious disease caused by bacteria called Mycobacterium Tuberculosis. It primarily affects the lungs, but it can also affect organs in the central nervous system, lymphatic and the circulatory systems. An estimated 14 million people worldwide are infected with active tuberculosis (TB), which is a disease affecting mainly young adults. The vast majority of deaths from TB are in the developing world and TB is considered to be the second most contagious disease to cause fatalities in the world.The Incidence of tuberculosis (per 100,000 people) in Yemen was last reported 49 in 2010, according to a World Bank report published in 2012. Incidence of tuberculosis is the estimated number of new pulmonary, smear positive, and extra-pulmonary tuberculosis cases. The aim of this study to surveymultidrug resistance tuberculosis (MDR TB) against four drugs used in Yemen (isoniazide, rifampicin, ethambutol and streptomycin) among new cases. Samples were collected from The National Tuberculosis Institute (NTI), Sana’a between Jan. and Sept. 2013. About 731 of 2226 of patients from different governances that referred to NTI were reported asMycobacterium tuberculosis positive cultures.209 of 731 were showed mono or multidrug resistance, the others either negative or contaminated. 201 of 209 cultures were obtained from new cases and 8 previously treated. The prevalence of any resistance to four drugs was 63.7% (95 CI 58.1-71.3) among new cases compared with 25%(95CI 7.1-59.1) among previously treated cases. The prevalence of MDR TB was shown 41.3% (95 %CI 34.5-48.1) among new cases compared with 12.5% (95% 2.2-47.1). Conclusion: there is highprevalence of MDRTB developed worldwide in the last three yearsdeveloped between new cases. This estimates public health problem not only in Yemen but around the world.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Doa'a Anwar Ibrahim, Al-Akhali A, Farouk A.Al-Qadasi The Prevalence of Antituberculosis Multidrug Resistance in Yemen 2013 International Journal of Scientific Research, Vol : 3, Issue : 7 July 2014

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