The Probability of Celiac Disease, indicated by high Anti TTG titer, in Omani Patients with Type 1 Diabetes Mellitus.

Dr Hamdi Saleh Al-Mutori; Dr Mazin Saleh Al-Rudaini; Dr Ali Al Reesi; Dr Salem Al Ghaithi; Dr Hamed Al Reesi

Volume : VIII, Issue : II, February - 2019

The Probability of Celiac Disease, indicated by high Anti TTG titer, in Omani Patients with Type 1 Diabetes Mellitus.

Dr Hamdi Saleh Al Mutori, Dr Mazin Saleh Al Rudaini, Dr Ali Al Reesi, Dr Salem Al Ghaithi, Dr Hamed Al Reesi

Abstract :

The coexistence of autoimmune disorders is not uncommon in clinical practice. Giving that both Type 1 diabetes mellitus (T1DM) and celiac disease (CD) are common autoimmune disorders, the association between the two conditions often exist. Many literatures demonstrated such association; however this associated was not studied thoroughly in Oman.

Methods: Patients with T1DM who were included in the study were tested serologically for probable CD using Anti–TTG antibody. Other nutritional parameters were also assessed. Information regarding patients� age, sex, duration of diabetes, presence of any symptoms suggestive CD and any family history of CD were gathered. Statistical Package for the Social Science (SPSS) was used to collect and analyze data.

Results: A total of 34 patients with T1DM visited the diabetic outpatient clinic in Suhar Hospital / Oman were included in the study during the study period. The majority of the patients (70.6%) were females and 29.4% were males. Seven patients had significantly high Anti–TTG which accounting for an incidence of 21.2%. The probability of positive CD for females was 71.4% compared to 28.6% for males, however, the difference wasn�t statistically significant. None of the celiac patients showed a weight change and the minority had diarrhea (14.3%). There was a significant association between BMI and CD (p=0.036).The BMI level was lower among positive celiac patients compared to negative celiac patients. Nutritional indicators showed no significant differences between those who are suspected to have CD and those who were not.

These findings suggest that the probability of having CD in patients with T1DM is high in Oman and screening for CD for all T1DM patients might be important.