The role of dexmedetomidine on induction dose of propofol-a comparative randomised controlled study

Dr Suhas M K; Dr Gururaj Tantry P

Volume : VII, Issue : XI, November - 2018

The role of dexmedetomidine on induction dose of propofol-a comparative randomised controlled study

Dr Suhas M K, Dr Gururaj Tantry P

Abstract :

General anaesthesia is a drug induced, controlled and reversible loss of consciousness during which patients are not arousable, even by painful stimulation. It is associated with impairment of the ability to independently maintain a patent airway. Dexmedetomidine a potent, highly selective α2 adrenoreceptor agonist possess desirable properties like sedation, analgesia, sympatholysis and reduces the anaesthetic requirement. Bradycardia and hypotension are the most common side effects of dexmedetomidine. Propofol, currently the most popular induction agent and has similar side effects compared to the above mentioned drug. Hence titration of the above mentioned drugs can minimize the adverse and retain the desired effects of their pairing. Hence this study was conducted with an objective of comp� and evaluating the effects of different doses of dexmedetomidine on induction dose of propofol.