IJSR - International Journal of Scientific Research

Seenivasan.M; Anandi.C; Gopalakrishnan.N

Volume : VI, Issue : IV, April - 2017

The Study of Clinical, Microbiological Profile and Risk Factors of Urinary Tract Infection in Renal Transplant Recipients

Seenivasan. M, Anandi. C, Gopalakrishnan. N

Abstract :

Renal transplantation has a better quality of life and better survival when compared to dialysis as a modality of management of end stage renal disease patients. Urinary tract infection (UTI) is a common complication after kidney transplantation. A retrospective case–control study was conducted in Department of Nephrology, Madras Medical College for 1 year from May2012 to April2013, to identify the microbiological profile and risk factors of UTI. Klebsiella oxytoca was the organism commonly isolated followed by E.coli. Recurrent UTI occurred in 6 patients commonly due to klebsiella oxytoca. There was no correlation with diabetes (p=1.0), cytomegalovirus disease (p=0.78) and anti rejection therapy (p=0.46) with incidence of UTI in renal transplant recipients. There was increased incidence of UTI in patients with hepatitis C virus (HCV) co–infection (p=0.0091). The graft outcome (p=0.037) was poor in those with UTI. Structural and functional abnormalities of urinary tract increase the risk of UTI, except vesico ureteric reflux (VUR), and Horse Shoe kidney. Graft pyelonephritis is associated with poor outcome.