The Study of Prevalence of Subclinical  Hypothyroidism (SCH) in Patients with Well  Controlled Type 2 Diabetes Mellitus

Dr.Mahesh S. Neginhal; Dr.Praveenkumar Devarbhavi; Dr.Vasudeva Murthy; Dr.Aruna T

Volume : II, Issue : VII, July - 2013

The Study of Prevalence of Subclinical Hypothyroidism (SCH) in Patients with Well Controlled Type 2 Diabetes Mellitus

Dr. Mahesh S. Neginhal, Dr. Praveenkumar Devarbhavi, Dr. Vasudeva Murthy, Dr. Aruna T

Abstract :

Thyroid disease is a pathological state that can adversely affect metabolic parameters of diabetes mellitus like LDL cholesterol triglycerides and blood glucose levels. The relation between Type 2 DM and thyroid dysfunctions is not clearly identified. In diabetics due attention is not given in trying to detect presence of thyroid dysfunctions. It is important because the present consensus of opinion is to treat subclinical hypothyroidism (SCH). Hence there is need for screening for SCH in diabetic patients. Objective: To identify the prevalence of SCH in Type 2 Diabetes Mellitus (T2DM) patients with good glycemic control. Study design: Cross sectional study design. Study setting:S.S.Institue of medical science and research centre Davanagere. Study participants: The thyroid profile was done on 60 eligible patients who fulfilled the inclusion criteria and exclusion criteria. Statistical Analysis: The results were analyzed using chi-square test and tests of proportion. Results: Out of sixty patients, 17(28.35%) were detected to have thyroid dysfunction. 43 (71.6%) were euthyroid, 11 (18.33%) were SCH, 5(8.33%) had primary hypothyroidism and 1 patient was subclinical hyperthyroid. Thus the prevalence of SCH was 18.33% in this study. Females had higher prevalence of SCH than males (29.6% vs9.09%) P value was found to be statistically significant. Prevalence of SCH was more in the > 50 years age group as compared to ≤50years (22.2% V/s 6.69%) P value was not significant. Prevalence of SCH increased with increasing duration of DM. Prevalence of SCH was higher in patients with BMI >25, hypertensive diabetics and those with associated IHD(Ischaemic Heart Disease) as compared to those with BMI ≤ 25, normotensive diabetics and those without IHD respectively. Conclusion: The study shows 18.33% prevalence of SCH in T2DM patients with good glycemic control. This finding indicates that SCH was common in T2DM patients and a need for screening for the same in them