To assess Multidrug Resistant Tuberculosis (MDR-TB) and its treatment outcomes in a tertiary hospital in Punjab, India

Ripudaman Singh; Mannat Kaur Bhatia; Akashdeep Singh; Dr.Vishal Chopra

Volume : VII, Issue : VI, June - 2018

To assess Multidrug Resistant Tuberculosis (MDR-TB) and its treatment outcomes in a tertiary hospital in Punjab, India

Ripudaman Singh, Mannat Kaur Bhatia, Akashdeep Singh, Dr. Vishal Chopra

Abstract :

BACKGROUND –The advent of MDR TB threatens to de–stabilize the Tuberculosis control programmes all over the globe. MATERIALS AND METHODS– It was a retrospective cohort study. Microsoft Excel 2007 was used to analyze medical records.RESULTS–Out of 113 patients under study, 68 (60.17%) patients were successfully treated (cured 50 [44.24%] + treatment completed 18 [15.92%]). 22(19.46%) patients died, 10 (8.84%) failed, 10 (8.84%) defaulted and 2 (1.76%) were transferred out to other sites. For the rest, treatment was discontinued or 1(0.88%) was shifted to XDR. 41 (36.28%) converted their sputum culture to negative (�initial favorable response�) after the intensive phase of therapy. CONCLUSION– The successful treatment rate is still low though higher than the WHO reported data of MDR–TB 2014 onwards. MDR–TB is a challenge which must be undertaken by judicious use of appropriate drugs, supervised individualized treatment and follow–up which constitute the key factors for successful management of these patients.