To Compare the Lipid Profile in  Uncomplicated and Complicated Type  Ii Diabetes Mellitus (Niddm)

Dr. Bhushan  Damodhar  Dudhane

Volume : II, Issue : IX, September - 2013

To Compare the Lipid Profile in Uncomplicated and Complicated Type Ii Diabetes Mellitus (Niddm)

Dr. Bhushan Damodhar Dudhane

Abstract :

Introduction – The incidence of diabetes mellitus (DM) in human population has reached to epidemic proportions worldwide. In long standing diabetes there are various complications such as microvascular, macrovascular and neuropathic. This has been attributed to the hyperlipemia and hypercholesterolemia of chronic diabetes state .The present study was undertaken to assess the correlation between disordered lipid profile (i.e. dyslipdemia) and progression of disease (i.e. type II DM ). Aims and objectives –1. To estimate the serum lipid profile in control, uncomplicated type 2 DM group and complicated type 2 DM group.and. to compare the serum lipid profile amongst control, uncomplicated type 2 DM group and complicated type 2 DM group. Materials and methods – Total 90 subjects (both male & female) of age group 35–60 yrs. were selected for study. Lipid profile was estimated by CE–CO–PAP method (for total cholesterol & HDL–c estimation) & by GPO–PAP End pt. method (for TG estimation). Observations and results –It was found that average serum values of lipid profile were significantly increased (except HDL) in complicated type 2 DM as compared to uncomplicated group. Also, as compared to control group, all the values of lipid profile (except HDL) were significantly increased & HDL–c was significantly decreased in complicated group. Conclusion – The study indicated a definite positive correlation between dyslipidemia and development of chronic complications. (especially macroangiopathic).