To study the difference in estimated glomerular filtration rate (eGFR) and total kidney volume (TKV) between newly diagnose DM type 2 and healthy control

Krishan Kant Sharma; Aradhana Sharma; Puneet Saxena

Volume : VII, Issue : II, February - 2018

To study the difference in estimated glomerular filtration rate (eGFR) and total kidney volume (TKV) between newly diagnose DM type 2 and healthy control

Krishan Kant Sharma, Aradhana Sharma, Puneet Saxena

Abstract :

Material and Method: This was a hospital based observational case control study conducted on 66 diabetics case group and 66 healthy control group. A detailed history and physical examination were recorded. Laboratory investigations done were – fasting and postprandial blood sugar, and glycosylated haemoglobin. eGFR was estimated by the creatinine clearance and TKV was determined by ultrasonography.

Result:

The mean eGFR (ml/min) in cases and control was 106.57�10.69 and 92.909�4.62 respectively, which was statistically significant (p<0.001).The mean total kidney volume (ml) in cases and control was 125.81�15.508 and 91.15�3.66 respectively, which was also statistically significant (p<0.001).The eGFR and TKV both were found to be significant in this study.

Conclusion:

We observed that newly diagnosed cases of diabetes have significantly higher eGFR and total kidney volume as compared to non– diabetic healthy population. Hence eGFR and total kidney volume can be predicted to a certain degree, i.e. there is a gradual developing diabetic nephropathy.