To study the levels of Serum Lipoprotein (a) in patients with Essential Hypertension

Dr Aher Sangeeta; Mr.Sudhir Dhokar; Dr.Ashok kumar; Mrs.Vasanthi Iyengar

Volume : VIII, Issue : IV, April - 2019

To study the levels of Serum Lipoprotein (a) in patients with Essential Hypertension

Dr Aher Sangeeta, Mr. Sudhir Dhokar, Dr. Ashok Kumar, Mrs. Vasanthi Iyengar

Abstract :

Aim: Aim of the study was to find out the level of serum lipoprotein (a) in healthy and hypertensive subjects and role of serum lipoprotein (a) as an independent marker of cardiovascular risk in patients with essential hypertension and to find its association with blood pressure and lipid profile Material and Method: 50 patients with essential hypertension and 50 apparently healthy subjects were included in the study. Sera were collected from them and serum Lipoprotein (a) [Lp (a)] with immunoturbidometric assay and lipid profile were measured by standard biochemical methods on automated chemistry analyzer. Unpaired t–test was used to assess the significant difference in the means of the studied variables in the different groups. Result: Serum lipoprotein (a) was found to be significantly increased (p<0.001) in hypertensive patients (36.52 � 9.34 mg/dl) as compared to healthy individuals (17.96 � 8.42 mg/dl). Total cholesterol, LDL, triglycerides were significantly increased (p<0.001) and HDL was significantly decreased (p<0.001) in cases compared to controls. Conclusion: Elevated lipoprotein (a) in hypertensive patients can be an independent risk factor for development of cardiovascular disease