To study the prevalence of impaired Oral Glucose Tolerance Test in drug naive schizophrenic patients in comparison with healthy controls

Dr Richa Choudhary; Dr Pali Rastogi; Dr Ram Ghulam Razdan; Dr Vijay Niranjan

Volume : VIII, Issue : IX, September - 2019

To study the prevalence of impaired Oral Glucose Tolerance Test in drug naive schizophrenic patients in comparison with healthy controls

Dr Richa Choudhary, Dr Pali Rastogi, Dr Ram Ghulam Razdan, Dr Vijay Niranjan

Abstract :

Background: Schizophrenia is a severe illness. Rate of type 2 diabetes is about 2–3 times higher as compared to the general population. We are intended to perform the oral glucose tolerance test in drug–na�ve schizophrenia patients & determine whether the disease itself increase the risk of impaired glucose tolerance or not, it will guide the antipsychotic treatment & help in minimizing the risk & complications of metabolic impairment. Material & Method: Two group i.e. drug na�ve schizophrenia patients &healthy controls were recruited from OPD of psychiatry, M.Y and mental hospital, Indore. Assessment was done with oral glucose tolerance test. Results:Mean fasting and 2hr blood sugar among cases and control were 81.2�15.9 & 116.08�25.7 and 83.1�12.1. & 115.7�20.2 respectively. Prevalence of impaired oral glucose tolerance test(OGTT) among cases & control was 15% and 3.3% respectively. Conclusion: OGTT was significantly impaired in cases as compared to controls