TO STUDY THE PREVALENCE OF PULMONARY HYPERTENSION AMONGST CKD PATIENTS IN BUNDELKHAND REGION.

Dr. Rambabu Singh; Dr. Vijay Kumar Gupta; Dr. Zaki Siddiqui; Dr. Ramendra Singh Tomar; Dr. Prateek Saxena

Volume : IX, Issue : V, May - 2020

TO STUDY THE PREVALENCE OF PULMONARY HYPERTENSION AMONGST CKD PATIENTS IN BUNDELKHAND REGION.

Dr. Rambabu Singh, Dr. Vijay Kumar Gupta, Dr. Zaki Siddiqui, Dr. Ramendra Singh Tomar, Dr. Prateek Saxena

Abstract :

Introduction: Pulmonary hypertension (PH) is a recently recognized complication of chronic kidney disease (CKD), especially in end–stage renal disease. It has prevalence estimates of 30%–50% and is an independent predictor of increased mortality in CKD patients. Aim: The aim of this study the clinical and diagnostic profile of pulmonary hypertension in patients of CKD treated with different strategies of management i.e. (Conservative, haemodialysis and CAPD). Material and methods: Our study is a prospective observational study & will be conducted in M.L.B. Medical College, Jhansi, including a minimum sample size of 100 Chronic Kidney Disease (CKD) patients who are coming to Departments of General Medicine, M.L.B Medical College, Jhansi (U.P.) in our outdoor and indoor during the period from March. 2018 to Oct.2019 as per our selection criteria. Result: Out of the total 120 patients included in the study, 43 (35.83%) patients had PH. Majority, 21 (48.83%) of CKD patients showed mild PASP followed by 15 (34.88%) patients moderate group and 7 (16.27%) severe PH. There was no effect of age on prevalence of PH. Out of the total 43 patients with PH 31 (72.09%) were males. PH was more common in males than females and statistically significant (p =.022). There was statistically significant association between CKD stages and PH (p <.001). None of the patients in CKD stage II revealed PH, while 1(2.32%), 3(7%), and 39 (90.7%) patients of CKD stage III, IV, and V, respectively, had PH. 20 out of 34 diabetics (58.82%) had PH whereas 26 out of 47 hypertensive�s (55.31%) had PH. There was a strong association between diabetes and hypertension with PH (p <.001) Conclusion: Mortality of CKD Patients with PH was strongly associated with presence of HF, HTN, age>60 years(63.63%), severity of PH (71.42%0, Hb <10gm/dl (50%),BUN>45mg/dl(45.6%), S.creatinine >5mg/dl(44.82%) and Ca x P product >55mg2/dl2 (51.85%) and statistically significant (p<.05)