Volume : V, Issue : X, October - 2016

Toxicity and mechanism of action of Paracetamol

M Fadil Salmani, Amit Kumar

Abstract :

 Aim: To study the use of paracetamol and ibuprofen for pediatrics pain and fever. Study selection: Data from original studies on pharmacogenomics, pharmacokinetics and pharmacology of paracetamol were included in the analysis. Results: More published studies are required to comprehensively define the pharmacology and phamacokinetics of paracetamol and ibuprofen in paediatrics. Conclusion: An understanding of drug metabolic processes during ontogeny may enable predictions about the capacity of children to cope with medications. Pharmacogenomic screening may help elucidate the inter–individual variation in drug metabolism and pharmacokinetics.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

M Fadil Salmani, Amit Kumar Toxicity and mechanism of action of Paracetamol International Journal of Scientific Research,Volume : 5 | Issue : 10 | October 2016

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