Treatment of Periodontal Intrabony Defect with Platelet Rich Fibrin and Bone Replacement Graft: A Case Report

Vishnu JS; Arya KS; Arun Sadasivan; Elizabeth Koshi

Volume : V, Issue : IX, September - 2016

Treatment of Periodontal Intrabony Defect with Platelet Rich Fibrin and Bone Replacement Graft: A Case Report

Vishnu Js, Arya Ks, Arun Sadasivan, Elizabeth Koshi

Abstract :

The goal of periodontal therapy has always been the regeneration of the lost attachment apparatus. Regeneration is thought to partially mimic developmental mechanisms, which requires a coordinated orchestration of cellular events such as proliferation, migration and differentiation. Regeneration has been defined as the reproduction or reconstitution of a lost or injured part to restore the architecture and function of the periodontium. Regenerative potential of platelets was introduced in 1974 and found that growth factors are released after activation from the platelets trapped within fiin matrix, and have been shown to stimulate the mitogenic response in the periosteum for bone repair during normal wound healing. Choukroun�s platelet rich fiin (PRF) is a fiin matrix in which platelet cytokines and cells are trapped which are released after a certain time, and that can serve as a resorbable memane. In the present case combination of PRF and Bone graft [Demineralised Bone Matrix (DMBM)] was used to treat the periodontal intra bony defect.