UNDERSTANDING TRENDS OF TRANSFUSIONTRANSMISSIBLE INFECTIONS AMONG VOLUNTARY BLOOD DONORS.

SAILI JADHAV; DR. MRS. S.H.KHAPARDE

Volume : V, Issue : IX, September - 2016

UNDERSTANDING TRENDS OF TRANSFUSIONTRANSMISSIBLE INFECTIONS AMONG VOLUNTARY BLOOD DONORS.

Saili Jadhav, Dr. Mrs. S. H. Khaparde

Abstract :

Context: Complications arising out of improperly tested/screened blood units before transfusion are included as integral part of preventive medical mistakes. This retrospective study will show the epidemiological burden of voluntary blood donors carrying communicable diseases and transfusion transmitted diseases. Aims: The aim of this project is to observe the incidence of Syphilis, Hepatitis, HIV and malaria among voluntary blood donors in a blood bank. Settings and Design: This was a retrospective observational study conducted from 10th July 2013 till 10th July 2016. The equipment�s used: Blood was collected from satellite bag in 3 ml plain sterile vial and 2 ml in ethylene diamine tetra acetic acid (EDTA) vial. For the test procedures, we have a separate air conditioned laboratory equipped with all the necessaries like ELISA reader, ELISA washer, Incubator, multichannel and variable micropipettes etc. as per guidelines of Food and Drug Administration, Government of India. The blood unit was discarded as per guidelines of NACO whenever the pilot donor samples were found positive for any TTI. Methods and Material: Data was accumulated and analysed from blood bank records, pertaining to all voluntary donors who were screened for various TTIs using respective immunological methods. Then the tabulated seropositive donors were correlated with relevant epidemiological profiles Statistical analysis used: Descriptive statistics like mean, median, mode, percentage and proportion were used. Results: The epidemiological burden of infected blood collected amongst 4179 voluntary blood donors is of 1.9%. No donor has seropositivity for more than one infection in the study. The concurrent rates for seropositivity were highest for HbsAg (1.22%) followed by HCV (0.26), VDRL (0.23%), HIV (0.21) and Malaria (0%) in descending order. Conclusions: From the results it is concluded that the society still faces a big problem as HbsAg infection still continues to prevail and has high incidence of the disease in the general population. Seropositivity of HIV was found to be low in western and eastern Indian compared to northern and southern Indian. Implementation of strict selection criteria of donors as per guidelines laid down for blood banks in gazette notification of Government of India should be followed strictly