Volume : VI, Issue : VI, June - 2017

Urinary Bladder Carcinoma: A Clinicopathological Study

Mansi Sharma, K. C. Goswami, Sunil Gupta

Abstract :

 Introduction Urinary bladder cancer represents a global health problem. The objective of this study was to analyse the clinicopathological features of histologically confirmed urinary bladder carcinoma cases at a tertiary care hospital of Jammu. Material and Methods A total of 85 urinary bladder carcinoma specimens received in the department of Pathology, GMC Jammu over a period of 3 years w.e.f. 1st Nov. 2008 to 31st Oct. 2011were taken up for the study. Results The relative frequency of urinary bladder carcinoma among all the malignant tumours was 12.61%. TURBT specimens constituted 87% and cystectomy specimens constituted 13%.  The mean age was 59.15 ± 1.65 years with Male: Female ratio 7.5:1. 88% patients were smokers. Most common presenting symptom was hematuria. 83.01% of the growths were on lateral wall and posterior wall and 89.41% growths were grossly polypoidal/ papillary. Most common histological type of urinary bladder carcinoma found was urothelial carcinoma (97.65%) of which 19.27% showed divergent differentiation. Among TURBT urothelial carcinoma cases, 48.61% were high grade but among cystectomy specimen, majority were high grade (81.81%). Muscularis propria was present in 56.76% of TURBT specimens only, out of which 19.05% had pTa, 30.95% pT1 and 50% cases ≥pT2 stage.  Out of 11 cystectomy specimens, pTa, pT1, pT2, pT3 and pT4 stages were seen in 0, 3, 5, 3 and 0 cases respectively. Most (82.35%) of the low grade urothelial carcinomas were of pTa and pT1 stage, where as most (72.72%) of the high grade carcinomas were of ≥pT2 stage.   Conclusion Urinary bladder carcinoma is a common malignancy in patients attending our institution and is diagnosed at a relatively late stage when compared to the west. However, the situation can be improved by adopting proper education and screening programmes to increase awareness among people.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Mansi Sharma, K. C. Goswami, Sunil Gupta, Urinary Bladder Carcinoma: A Clinicopathological Study, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : VOLUME-6 | ISSUE-6 | JUNE-2017

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