Volume : VII, Issue : V, May - 2018

URINARY LACTATE TO CREATININE RATIO IN NEONATES BORN WITH RISK OF PERINATAL ASPHYXIA

Dr Satendra Singh Rajput

Abstract :

 Neonates with perinatal asphyxia are prone to development of hypoxic ischemic–encephalopahty (HIE). There are no reliable methods for prediction of HIE in these neonates. This study was designed to determine urinary lactate to creatinine ratio in neonates with perinatal asphyxia.A prospective study was carried out at NICU at Department of Pediatrics, G.R.Medical College Gwalior. 50 neonates born at > 36 weeks gestation with perinatal asphyxia, admitted in neonatal intensive care unit were taken as cases and 50 normal newborns with gestational age> 36 week included as control. We measured the ratio of lactate to creatinine in urine sample by colometric technique within 24 hr after birth both in cases and controls. All newborns were followed for 7 days during their stay in hospital for development of HIE. The results were correlated with the subsequent presence or absence of HIE.  The study revealed that mean urinary lactate to creatinine ratio during first 24 hours of life was higher in asphyxiated  neonates than control group.The grade of HIE correlated with the greater urinary lactate to creatinine ratio among cases. < clear="all" style="page–eak–before:always;mso–eak–type:section–eak" />

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr Satendra Singh Rajput, URINARY LACTATE TO CREATININE RATIO IN NEONATES BORN WITH RISK OF PERINATAL ASPHYXIA, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-5 | May-2018

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