URINARY MICROALBUMIN–CREATININE RATIO FOR EARLY DETECTION OF RENAL DAMAGE IN PATIENTS WITH TYPE II DIABETES

Amrita Malviya; Dr.A.D.Deepak; Apurva Jha; Aabha Malviya

Volume : V, Issue : II, February - 2016

URINARY MICROALBUMIN–CREATININE RATIO FOR EARLY DETECTION OF RENAL DAMAGE IN PATIENTS WITH TYPE II DIABETES

Amrita Malviya, Dr. A. D. Deepak, Apurva Jha, Aabha Malviya

Abstract :

<p>&nbsp;Objectives: The aim of the study was to assess urinary Micro albumin &ndash; Creatinine ratio for early detection of renal damage in patients with type II diabetes Study Design : observational &amp; prospective Place and Duration of Study : The study was carried out in Department of Biochemistry and department of Medicine, MGM Medical college, Navi Mumbai . Methodology : Total 90 subjects comprising of male and female aged between 33 to 77 years. They are divided into 3 groups . To estimate levels of urine albumin , urine creatinine and UACR ratio in subjects with Type II Diabetes mellitus with HbA1c levels &lt;7% (group I), in Type II Diabetes mellitus subjects with HbA1c levels between 7% to 9% (group II) and in Type II Diabetes Mellitus Subjects with HbA1c levels &lt;9% (group III) along with their follow up after three months. To evaluate the levels of fasting and postprandial plasma glucose and glycosylated Hb, in all the three groups and their follow up. Results : A significant (0.05) correlation exits between blood glucose levels and microalbumin creatinine ratio as the results show that with increase in FBS and HbA1c, Microalbumin creatinine ratio were increased in the follow up groups compared to baseline groups.</p>