Volume : VIII, Issue : IV, April - 2019

VASCULAR ENDOTHELIAL GROWTH FACTOR IN DENTIGEROUS CYST AND RADICULAR CYST : A COMPARATIVE STUDY

Dr Nidhi Khajuria

Abstract :

Background VEGF is a potent proangiogenic cytokine which acts on the vasculature by inducing the proliferation, differentiation and migration of vascular endothelial cells. Angiogenesis has been evaluated in various human lesions including east cancer, head and neck squamous cell carcinoma, lichen planus and ameloblastoma. Very little data were found on angiogenesis, as assessed by immunohistochemically in odontogenic cysts. The objective of the present study was to evaluate vascular endothelial growth factor (VEGF) expression in different types of odontogenic cysts Methodology: A retrospective study was carried out comprising a total of 18 cases , 9 cases of dentigerous cyst and 9 cases of radicular cyst. The sections were stained immunohistochemically with VEGF antibody and were evaluated for the presence, and intensity of the immunoreactive cells. Statistical analysis was carried out using Chi–square test to intercompare the VEGF expression between Dentigerous Cyst And Radicular Cyst Results: VEGF expression in the epithelium and connective tissue was significantly higher in compared to dentigerous and radicular cyst. Conclusion: The present study data supports the literature finding that angiogenesis can be important in the progression and enlargement of odontogenic cysts

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

VASCULAR ENDOTHELIAL GROWTH FACTOR IN DENTIGEROUS CYST AND RADICULAR CYST : A COMPARATIVE STUDY, Dr Nidhi Khajuria INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-4 | April-2019

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