VITAMIN D LEVELS IN EARLY PREGNANCY & PREGNANCY OUTCOMES

Dr Lata Rajoria; Dr Sangeeta Baror; Dr Sunita Hemani; Dr Jyotsna Vyas; Dr Dolly Marwai; Dr Shikha Bansal

Volume : VI, Issue : VIII, August - 2017

VITAMIN D LEVELS IN EARLY PREGNANCY & PREGNANCY OUTCOMES

Dr Lata Rajoria, Dr Sangeeta Baror, Dr Sunita Hemani, Dr Jyotsna Vyas, Dr Dolly Marwai, Dr Shikha Bansal

Abstract :

Aims and objectives – To find out the correlation of serum Vitamin D levels in early pregnancy and pregnancy outcomes (i.e. development of preeclampsia, birth weight, apgar score and NICU admissions etc.).

Material methods – This is a hospital based observational study done in Department of Obstetrics & SMS Medical College, Jaipur from March 2015 to Oct 2016 on 800 pregnant women attending the Antenatal clinic between 13–20 weeks gestation. Serum Vitamin D levels were assessed, all women were followed till delivery and three days after delivery.

Results – Serum 25(OH)D concentrations in early pregnancy were lower in women who subsequently developed preeclampsia as compared to women who did not developed preeclampsia [mean, 13.58 � 7.61 ng/ml, vs. 17.14�6.91ng/ml], Mean birth weight of newborns where the mothers was Vitamin D deficient came out to be 2.205 � 0.44 kg, for insufficient mothers mean birth weight was 2.59 � 0.407 kg while the mean birth weight was 2.83 � 0.49 kg in newborns of Vitamin D sufficient mothers. When APGAR score of neonate at 5 minute ≥7, mean maternal Vitamin D was 17.31 � 6.99 ng/ml whereas when APGAR score of neonate at 5 minute was < 7, mean maternal Vitamin D was 13.48 � 6.99 ng/ml. Mean maternal vitamin D level was 17.27 � 6.903 ng/ml in newborns who did not require NICU admission, whereas it was 13.87 � 7.22 ng/ml in those who required NICU admission.

Conclusion – Thus we conclude that Low serum Vitamin D levels in early pregnancy is associated with increased incidence of Preeclampsia low birth weight, low apgar score and increased NICU admissions.