Vitamin D Status in a Random Population: a Comparative Study Between Males and Females

Dr.D.Radhika chowdary; Mrs.Rohini Nellutla; Mr.K.Prasad Reddy

Volume : III, Issue : XII, December - 2014

Vitamin D Status in a Random Population: a Comparative Study Between Males and Females

Dr. D. Radhika Chowdary, Mrs. Rohini Nellutla, Mr. K. Prasad Reddy

Abstract :

Abstract-. Vitamin D deficiency is a well-known cause of rickets in children,osteomalacia and osteoporosis in adults. Worldwide, an estimated one billion people have inadequate levels of vitamin D in their blood, and deficiencies can be found in all ethnicities and age groups. Objective: The present study is a retrospective study and the objective is to compare the status of Vitamin D in a random population attending to a tertiary care hospital. Materials & methods: The study included a sample size of 320 subjects. Out of this 160 were male subjects and 160 were female subjects of age groups 20-75 years. Population above 75 years and below 20 years are excluded from the study. The vitamin D levels were compared seperately in females including 100 subjects, criteria being pre-menopause and post-menopause. 100 male subjects were compared with age above and below 50 years. Results: It is observed a higher prevalence of vitamin D deficiency is seen in general population, and deficiency being higher in females when compared to males (p<0.0001, r=0.100). No significant correlation was observed between males of above and below 50 years in this study (p=0.45, r=0.100). In females the prevalance of Vitamin D deficiency is found to be significantly higher in pre-menopausal than postmenopausal females (p<0.0001, r=0.170). Conclusion: The serum 25(OH)D concentration is the best indicator for vitamin D deficiency, insufficiency, sufficiency, and toxicity. There is a high prevalence of vitamin D deficiency and insufficiency, even in normal populations, and there is growing evidence for the contribution of low circulating 25(OH)D levels to the development of a wide range of chronic diseases.