Volume : V, Issue : X, October - 2015

A Case of Hashimoto Encephalopathy Presented with Seizure

Jayesh Patel, Chaiti Gandhi, Mayank Shah

Abstract :

 Hashimoto encephalopathy (HE) is a steroid–responsive but relapsing neuropsychiatric disorder associated with high titers of anti–thyroid antibody with or without thyroid dysfunction. Though numerous neurological manifestations are often associated with thyroid disorder, this entity is less documented. We are reporting a case of HE in a 63 year old female presenting with sudden onset focal seizure following an attack of mild fever. Other causes of vascular, infective, metabolic, autoimmune and toxic encephalopathy were excluded. MRI of ain revealed oedematous gyri of left medial temporal lobe with diffuse age related ain atrophy. Patient’s thyroid function tests were normal but anti–thyroid peroxidase (anti–TPO) antibody was significantly raised. EEG showed diffuse slow wave pattern. After suspecting diagnosis of HE, Intravenous methylprednisolone (one gram) given for five days. Patient regained consciousness slowly over a period of one week. HE must be kept in mind in comatose patients when other metabolic, infective and structural neurological causes have been excluded. Proper and timely treatment can salvage the patient.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Jayesh Patel, Chaiti Gandhi, Mayank Shah A Case of Hashimoto Encephalopathy Presented with Seizure Indian Journal of Applied Research, Vol.5, Issue : 10 October 2015

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