Volume : IX, Issue : IX, September - 2019

A case report of Acromegaly

Dr Jayprakash D Shirpurwar, Dr Jitendra Ingole

Abstract :

Acromegaly is a disorder related to excessive production of growth hormone and characterized by progressive somatic disproportional growth. It is most often diagnosed in adults in third to fourth decade of life. The main clinical features are oadened extremities hands and feet, widened thickened fingers, and thickened soft tissue. Patients have coarse facies with widened and thickened nose, prominent cheekbones, prominent forehead, thick lips and marked facial lines. Mandibular overgrowth is observed causing prognathism and teeth are widely spaced. The disease also has cardiovascular, respiratory, rheumatologic and metabolic consequences which determine its prognosis. The clinical diagnosis is confirmed biochemically by an increased serum GH following OGTT and insulin–like growth factor–I. Treatment is aimed at correcting or preventing tumour compression by excising the disease–causing lesion, and at reducing GH and IGF–I levels to normal values. First–line of treatment is transsphenoidal surgery. When surgery fails, medical treatment and/or radiotherapy can be used.

Keywords :

Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

A CASE REPORT OF ACROMEGALY, Dr Jayprakash D Shirpurwar, Dr Jitendra Ingole INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-9 | September-2019

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