Volume : IX, Issue : III, March - 2019

A CASE REPORT ON SPINAL MUSCULAR ATROPHY TYPE 1 ASSOCIATED WITH EXTENSIVE LOWER LIMB HYPOTONIA

Swetha M, Kiran Kumar. P

Abstract :

Spinal muscular atrophy (SMA) is a genetic motor neuron disease characterized by progressive degeneration of motor neurons. Here in, a 4.5 Months male child, born to healthy nonconsanguineous parents, has been ought with the chief complaints of weakness of both lower limbs since birthThere was no family history of neurological disease. On clinical examination, CVS function was normal. Fasciculations were seen in tongue. Respiratory muscles were mild affected. A diagnosis of SMA1 (deletion of SMN–I exons 7 and 8) was made on the basis of clinical presentation. No medical treatment was able to delay the progression, while In 2016, U.S. Food and Drug Administration approved nusinersen, treatment was improved muscle strength and movement in spinal muscular atrophy pediatrics and adults. Supporting therapy includes orthopedic care and mild physiotherapy

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

A CASE REPORT ON SPINAL MUSCULAR ATROPHY TYPE 1 ASSOCIATED WITH EXTENSIVE LOWER LIMB HYPOTONIA, Swetha M, Kiran Kumar. P INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-3 | March-2019

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