A CLINICAL STUDY OF ETIOPATHOGENESIS OF ACUTE KIDNEY INJURY PATIENTS, ADMITTED IN MEDICAL INTENSIVE CARE UNIT

Dr.Rakesh Patel; Dr. Santosh Singh; Dr.Anil Bharani

Volume : VIII, Issue : V, May - 2018

A CLINICAL STUDY OF ETIOPATHOGENESIS OF ACUTE KIDNEY INJURY PATIENTS, ADMITTED IN MEDICAL INTENSIVE CARE UNIT

Dr. Rakesh Patel, Dr. Santosh Singh, Dr. Anil Bharani

Abstract :

BACKGROUND: Before the advancement of modern medicine acute renal failure might be referred to as “UREMIC POISONING”. ARF due to ATN(acute tubular necrosis)was recognized in the 1940 in UK. Introduced by acute kidney injury network(AKIN),specific criteria exist for the diagnosis of AKI– Rapid time course(<48hrs), Reduction of kidney function, rise in s. cr. , absolute increase in s. cr. Of ≥0.3mg/dl, percentage increase in s. cr. Of ≥50%, reduction in urine output defined as <0.5ml/kg/hr for more than 6 hr.

AIMS AND OBJECTIVES:1– Analyses the principal causes ofAKI admitted in medical intensive care unit ,2– To study the correlation of etiology and outcome of the admitted patient in MICU with AKI.

MATERIALS AND METHOD: The present study was carried out among patients of MICUof sanjay Gandhi hospital rewa(m.p.). 319 AKI pts has been taken of different etiology and analyze there prevalence and prognostic value

RESULTS: the most common etiology of AKI is sepsis(31.03%) followed by GI fluid loss(18.99%), malaria(14.73%), cardiogenic shock(14.42%) etc.some pts also have postrenal pathology and hepatorenal syndrome(HRS) (4.07%). among the etiological point of view the HRS has highest mortality (69.23%) followed by sepsis (63.63%) and cardiogenic shock (63.04%).

CONCLUSION: the most common etiology of AKI in MICU pts is septicemia and acute GI fluid loss, malaria is also significant contributory in India.