A Comparative Clinical Study of Wound Healing  Properties of Aloe Vera Gel and Datura Metel Extract  in Traumatic Wounds in a Tertiary Care Hospital

V. P. Karthik; S. Seethalakshmi; Durairaj

Volume : III, Issue : VIII, August - 2013

A Comparative Clinical Study of Wound Healing Properties of Aloe Vera Gel and Datura Metel Extract in Traumatic Wounds in a Tertiary Care Hospital

V. P. Karthik, S. Seethalakshmi, Durairaj

Abstract :

The importance of traditional systems of medicine and of certain traditional medical practices has now been recognized all over the world. The present study was undertaken to compare the efficacy of Aloe vera gel and Datura metel extract in traumatic wounds and also evaluate and compare the safety and tolerability of Aloe vera and Datura metel in traumatic wounds. Both the drugs were applied topically 2–3 times a day in patients who were randomised into two groups; first group was given Aloe vera gel, second group was given Datura metel extract.Ulcer severity was graded based on Slough, Granulation tissue, Margin of the ulcers and Surrounding area of the ulcer. All the above parameters were assessed on baseline, 7th day, 14th day & 21st day. The slough reduction was more by 28% (p>0.05) in Datura metel group than in Aloe vera group. The improvement seen in granulation tissue of after 3 weeks of drug treatment were more in Datura metel group by 16.63% (p>0.05) when compared with Aloe vera group. The ulcer margin reduction was considered extremely significant in both the groups (p<0.05). Aloe vera showed 14.38% (p>0.05) more reduction in ulcer scoring for surrounding area than Datura metel. From the results it was concluded that Datura metel is a safe, effective and well–tolerated therapy and a proven alternative to Aloe vera for patients with traumatic wounds.