A COMPARATIVE EVALUATION OF INTRAVENOUS MAGNESIUM SULPHATE IN TWO DIFFERENT DOSES FOR PREVENTION OF POSTOPERATIVE PAIN AFTER INFRAUMBILICAL SURGERIES UNDER SPINAL ANAESTHESIA.

Dr Pooja S Kohat; Dr Kamalraj Singh; Dr Jitendra Agrawal; Dr Dilip Kothari; Dr Bhanu Choudhary

Volume : VI, Issue : III, March - 2016

A COMPARATIVE EVALUATION OF INTRAVENOUS MAGNESIUM SULPHATE IN TWO DIFFERENT DOSES FOR PREVENTION OF POSTOPERATIVE PAIN AFTER INFRAUMBILICAL SURGERIES UNDER SPINAL ANAESTHESIA.

Dr Pooja S Kohat, Dr Kamalraj Singh, Dr Jitendra Agrawal, Dr Dilip Kothari, Dr Bhanu Choudhary

Abstract :

BACKGROUND: In a randomized, double–blind, prospective study, we have evaluated the effect of i.v. infusion of magnesium sulphate in two different doses during spinal anaesthesia, postoperative analgesia and postoperative analgesic requirements in patients undergoing infra umbilical surgeries. AIM: A comparative evaluation of intravenous magnesium sulphate in two different doses for prevention of postoperative pain after infraumbilical surgeries under spinal anaesthesia. METHODS AND MATERIAL: 90 female patients of ASA grade I and II of the age group 20–40 yrs, posted for infra umbilical surgeries (lower segment caesarean section) under spinal anaesthesia were selected after pre anaesthetic fitness. Randomly patient were divided into 3 groups (n = 30 patients each) group MS, group MS–30 and group MS–50 to receive 100 ml of 0.9% Normal saline, Magnesium sulphate 30 mg kg–1 in 100 ml of 0.9% Normal saline and Magnesium sulphate 50 mg kg–1 in 100 ml of 0.9% Normal saline respectively to be given over 15 min,60 min after performing spinal anaesthesia. After surgery, rescue analgesia in form of inj.tramadol 100 mg i.v was provided for the patients. The Postoperative pain scores, Rescue analgesic consumption, and incidences of nausea, vomiting, dyspnoea, respiratory depression, chest pain, sedation, shivering, dysrrhythmia, adycardia, and hypotension evaluated immediately after surgery, at 30 min, 1, 2, 3, hr after surgery. STATISTICAL ANALYSIS: Results were expressed as mean and standard deviation. P value of <0.05 was considered statistically significant. RESULTS: IV Magnesium sulphate 50 mg kg–1 bolus significantly prolonged duration of analgesia, superior quality of analgesia (lower VAS) and significant reduction in postoperative analgesic requirement than 30 mg kg–1 under spinal anaesthesia. No significant hemodynamic and respiratory instability occurred with two doses of Magnesium sulphate used. CONCLUSION: I.V. magnesium sulphate administration during spinal anaesthesia improves postoperative analgesia without any notable complications.