A Comparative Study Between Intranasal Dexmedetomidine and Intranasal Ketamine As A Premedication in Paediatric Surgeries

DR RAJALAKSHMI J; DR LOKESH KUMAR K S; DR SANTOSH KUMAR

Volume : IV, Issue : XII, December - 2014

A Comparative Study Between Intranasal Dexmedetomidine and Intranasal Ketamine As A Premedication in Paediatric Surgeries

Dr Rajalakshmi J, Dr Lokesh Kumar K S, Dr Santosh Kumar

Abstract :

<p>Background: This prospective, randomized, double&ndash;blind study was designed to evaluate the use of intranasally administered dexmedetomidine vs intranasal ketamine as a premedication in children undergoing< /> general surgeries< /> Methods: 60 children of ASA physical status I and II, between the ages 2 to 8yrs were randomly assigned to 2groups.< /> Group D&ndash; Patients received intranasal dexmedetomidine (2&mu;g/kg). Group K&ndash; Patients received intranasal ketamine< /> (6mg/kg). At 45 minutes after intranasal dose, sedation, ease of separation and IV cannula acceptance, was evaluated< /> Results: The Group K had a median onset of action of 11.67 minswhen compared to Group D of 29.47 mins.57% of< /> children in Group Kbecame significantly asleep when compared to 33% in Group D. (p=0.037). parental separation was< /> excellent in Group K when compared to Group D. (33.33% vs 10%) (P&lt;0.005 ). intravenous cannula acceptance was< /> good in Group Kwhen compared to Group D (60% vs 16%).< /> Conclusion: Ketamine (6 mg/kg) via intranasal route is better than dexmedetomidine(2&mu;g/kg), in terms of better sedation, parental separation and IV cannula acceptance</p>