Volume : VIII, Issue : IV, April - 2018

A COMPARATIVE STUDY OF ANALGESIC EFFICACY OF INTRATHECAL DEXMEDETOMIDINE 5mcg AND 10mcg AS ADJUVANTS TO BUPIVACAINE IN SPINAL ANESTHESIA FOR LOWER LIMB ORTHOPAEDIC SURGERIES

Dr. J. Sudheer Kumar, Dr. A. Christopher

Abstract :

Background: Dexmedetomidine a selective α2 adrenergic agonist is gaining popularity as adjuvant to spinal anesthesia

 

Aim: The purpose of study was to compare two different doses of dexmedetomidine in terms of onset of action, duration of sensory and motor block,hemodynamic effects and adverse effects

 

Methods :60 patients were recruited and randomly divided into 2 groups.

Group A– Dexmedetomidine 5mcg.

Group–B: Dexmedetomidine 10mcg and received 5mcg and 10 mcg respectively in combination with bupivacaine through intrathecal route. Duration of spinal anaesthesia,sedation score and complications were noticed and recorded in both groups.

 

Results: There was an increase in duration of sensory block with increase in dose as it was 6.12 ± 1.2 in Group B and 6.02 ± 0.5 in Group A. However neither statistical nor clinical significance between the 2 groups was observed (P>0.05). On other hand there was neither statistical nor clinical significance regarding onset,recovery time or complications.

Conclusion: Dexmedetomidine 5mcg seems to be an attractive alternative when compared to 10 mcg as an adjunct to spinal bupivacaine in lower limb orthopaedic surgeries.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr.J.Sudheer Kumar, Dr.A.Christopher, A COMPARATIVE STUDY OF ANALGESIC EFFICACY OF INTRATHECAL DEXMEDETOMIDINE 5mcg AND 10mcg AS ADJUVANTS TO BUPIVACAINE IN SPINAL ANESTHESIA FOR LOWER LIMB ORTHOPAEDIC SURGERIES, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-4 | April-2018

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