Volume : V, Issue : X, October - 2015

A COMPARATIVE STUDY OF DEXMEDETOMIDINE AND MIDAZOLAM FOR INTRAVENOUS SEDATION IN DENTAL PROCEDURES

Dr. Ekta Bhanot, Dr. Khushali Tilvawala, Dr. Vibhuti Shah

Abstract :

<p> AIMS AND OBJECTIVES: To compare the efficacy and safety of dexmedetomidine and midazolam as an intravenous sedative agent for dental procedures under local anaesthesia. MATERIAL AND METHODS: This randomized double blind study compared dexmedetomidine and midazolam for intravenous sedation during various dental procedures like wisdom tooth extraction, implant surgeries and minor soft tissue surgeries. Sixty patients received either dexmedetomidine up to 1 mcg/kg or midazolam up to 5 mg, which was infused until the Ramsay sedation score was four or the maximum dose limit was reached. Intra operative vitals, postoperative pain scores and analgesic consumption, amnesia and satisfaction scores for patients and surgeon were recorded. RESULTS: Sedation was achieved by median doses of 47 mcg (39–52) or 0.88 mcg/kg (0.75–1.0) dexmedetomidine in Group D, or 3.6 mg (3.3–4.4) or 0.07mg/kg (0.055–0.08) midazolam in Group M. Heart rate and blood pressure during surgery were lower in dexmedetomidine group. There was no significant difference in satisfaction or pain scores. Midazolam was associated with greater amnesia. CONCLUSION: Dexmedetomidine produces comparable sedation to midazolam</p>

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Ekta Bhanot, Khushali Tilvawala, Vibhuti A.Shah A Comparative Study of Dexmedetomidine and Midazolam For Intravenous Sedation in Dental Procedures Indian Journal of Applied Research, Vol.5, Issue : 10 October 2015

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