A COMPARATIVE STUDY OF HRV ANALYSIS IN REFLUX POSITIVE AND REFLUX NEGATIVE PATIENTS WITH ACID PEPTIC DISEASE

Dr.S.Subhashini; Dr.C.N.Angel Deepa

Volume : X, Issue : I, January - 2020

A COMPARATIVE STUDY OF HRV ANALYSIS IN REFLUX POSITIVE AND REFLUX NEGATIVE PATIENTS WITH ACID PEPTIC DISEASE

Dr. S. Subhashini, Dr. C. N. Angel Deepa

Abstract :

The Aim of the study was to investigate a possible relationship between gastroesophageal reflux and autonomic imbalance in patients symptomatic for acid peptic disease using spectral analysis of HRV. Demographic parameters such as Age, weight, Body Mass Index, resting heart rate and blood pressure were obtained. 24 hour pH analysis was done to identify reflux positive group. Frequency domain and time domain measures as well as demographic variables were compared between reflux positive(n=23) and reflux negative group(n=24). The results revealed simultaneous decrease of LF component and increase of HF in the reflux positive patients. We demonstrated the evidence of functional ANS disturbances, which may be responsible for changing the HRV parameters of the frequency and time domain analysis in GERD patients. The disturbances mentioned above are supposed to influence the normal modulation of the vagaltone, which is vital for maintaining the physiological functions of oesophageal sphincter.