Volume : X, Issue : II, February - 2020

A Comparative Study Of Lipid Profile In Diabetes Mellitus Patients With And Without Diabetic Retinopathy

Tanushree Mondal, Arpita Naskar, Mahesh Chattopadhyay, Udayaditya Mukhopadhyay

Abstract :

PURPOSE: 1. To study the relationship between the severity of diabetic retinopathy and serum lipid levels. 2. To evaluate the relationship between serum lipid levels, diabetic retinopathy changes including CSME. METHODS: 100 diabetic patients without retinopathy (group A), 100 diabetic patients with retinopathy (group B), 100 nondiabetic patients with no retinopathy as control (group C) according to ETDRS chart were studied. Total cholesterol(TC), triglycerides(TG), high–density lipoprotein(HDL), low–density lipoprotein (LDL), very–low–density lipoprotein (VLDL) and Fasting plasma glucose (FPG), 2hr Plasma Glucose (2hr PG), HbA1C (glycosylated hemoglobin) levels were compared among the groups. RESULTS: The groups were age and gender matched (P= 0.474 and P= 0.84 respectively, one–way ANNOVA test ). The mean duration of diabetes was higher in Group A than Group B (P= <0.0001; P= >0.0001 respectively). The Body Mass Index is higher in both Group A and Group B than Group C (P= <0.0001; P= <0.0001 ; P= >0.0001 respectively). The mean FBS, PPBS, and HbA1C were higher for Group A and B than the control group C (P= <0.0001; P= <0.0001;P= >0.0001 respectively). The mean TG and VLDL are higher in Group A and B than Group C (P= 0.043; P= 0.044 respectively). The mean HDL was lower in Group A than the other two (P=0.674). Out of 56 cases of CSME among diabetic patients, 44(78.5%) had CSME in both eyes which were significantly higher (Z=6.87;p<0.0001). No CSME was found among Group B and C. CONCLUSION: Serum Lipid levels were significantly associated with the severity of DR and the existence of CSME in those patients.

Keywords :

Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

A COMPARATIVE STUDY OF LIPID PROFILE IN DIABETES MELLITUS PATIENTS WITH AND WITHOUT DIABETIC RETINOPATHY, Tanushree Mondal, Arpita Naskar, Mahesh Chattopadhyay, Udayaditya Mukhopadhyay INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-2 | February-2020

Number of Downloads : 294

References :