Volume : VI, Issue : IV, April - 2016

A comparative study of Serum hCG concentration in Pregnancy induced hypertensive and normotensive women in 3rd trimester of pregnancy

Tapas Paul, Jadab Kishore Phukan, Kailash Bhattacharyya

Abstract :

 Background: Hypertensive disorders are among the commonest and unpredictable medical disorders during pregnancy contributing significantly high to maternal and perinatal morbidity and mortality. Human chorionic gonadotropin (hCG) is a glycoprotein that is produced during pregnancy by the developing emyo and later by the syncytio trophoblast of the placenta mainly. hCG is found to be abnormally raised in the urine and serum of pregnant women with pregnancy induced hypertension. Aims: To evaluate the level of serum human chorionic gonadotropin and its correlation with pregnancy induced hypertension and to compare the serum β hCG level between study and control group. Materials and Methods: The study was carried out in the department of Biochemistry, Assam Medical College and Hospital, Diugarh. The study includes two group cases and controls. The cases included in the study were taken from Obstetrics and Gynaecology Department, Assam Medical College & Hospital during the period of study. The cases comprised of 50 clinically established cases of Pregnancy Induced Hypertension (PIH) in their third trimester and the control group comprised of 50 cases of normotensive pregnant patients in the third trimester. Results: The differences of mean serum β hCG concentration in cases and in controls were statistically very highly significant (p < 0.001). It is also found that there is positive correlation between serum β hCG concentration with Blood pressure levels both systolic and diastolic pressure. Conclusion: Pregnant women with pregnancy induced hypertension have higher level of serum β hCG in comparison to normotensive women

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Tapas Paul, Jadab Kishore Phukan, Kailash Bhattacharyya A comparative study of Serum hCG concentration in Pregnancy induced hypertensive and normotensive women in 3rd trimester of pregnancy Indian Journal of Applied Research, Vol.6, Issue : 4 April 2016

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