A COMPARISON BETWEEN PAPAIN AND UREA DERIVATIVE AND EUSOL IN THE OUTCOME OF WOUND HEALING IN DIABETIC TROPHIC ULCERS

Mohammed Nadeem Nazim; Natasha Mathias

Volume : VIII, Issue : I, January - 2018

A COMPARISON BETWEEN PAPAIN AND UREA DERIVATIVE AND EUSOL IN THE OUTCOME OF WOUND HEALING IN DIABETIC TROPHIC ULCERS

Mohammed Nadeem Nazim, Natasha Mathias

Abstract :

INTRODUCTION: Diabetic foot ulcer is a major disabling complication of diabetes which often precedes amputation of the limb. The DFU requires a long healing time and a multidisciplinary therapy, such as control of blood sugar levels, daily treatment of wounds, proper antibiotic therapy, and surgical revascularization.

METHODOLOGY: Study was conducted in 80 patients who were diabetics with foot ulcers.

Diabetics with foot ulcers along with peripheral vascular disease/ underlying osteomyelitis and gangrene were excluded from the study. Papain and urea derivative (Deidase) and EUSOL are used to create a moist and clean wound environment to promote granulation, autolytic processes, angiogenesis and more rapid migration of cells across the wound.

RESULT: Deidase was found to be a better agent in wound healing for diabetic foot infections in comparison to EUSOL as seen in accordance to PUSH scoring.

Cost is comparatively more with Deidase dressings. Individuals having a good nutritional status had a better improvement in their wound healing when compared to individuals having poor nutritional status.

CONCLUSION: There is no co–relation between duration of ulcer and rate of healing of ulcer. Wound dressing with Papain and Urea derivative (Deidase) was found to reduce the load of slough quicker when compared to EUSOL.