A COMPARISON OF IV DEXMEDETOMIDINE AND MIDAZOLAM FOR SEDATION IN PATIENTS UNDER NEURAXIAL ANAESTHESIA

Dr. Ajaykumar Anandan; Dr. Juvairiya Banu

Volume : IX, Issue : XII, December - 2019

A COMPARISON OF IV DEXMEDETOMIDINE AND MIDAZOLAM FOR SEDATION IN PATIENTS UNDER NEURAXIAL ANAESTHESIA

Dr. Ajaykumar Anandan, Dr. Juvairiya Banu

Abstract :

BACKGROUND: Spinal anesthesia is the most widely practiced method of anesthetizing a patient for majority of the infraumbilical surgeries. Several drugs have been used as an adjuvant to prolong the intrathecal block which can be given either intrathecally or intravenously. This study aims at compå the efficacy of iv dexmedetomidine and midazolam for sedation for patients under neuraxial anesthesia. MATERIALS AND METHODS: It was a randomized study. 60 patients were enrolled in this study of either sex age group between and American society of Anesthesiology(ASA) physical satus I, II&III Study was conducted after getting informed and written consent. Patients were divided into two groups GROUP D(iv dexmedetomidine) and GROUP M(iv midazolam). Various parameters like HR, MAP, were recorded. Sedation score was recoded using ramsay sedation score 10 minutes, 15 minutes, 20 minutes, 35 minutes, 50 minutes, 65 minutes & 80 minutes. RESULTS: Among the cases, with respect to the Ramsay Sedation Score, both the groups were statistically comparable and were statistically significant (P < 0.05) after 10 minutes, 15 minutes, 20 minutes, 35 minutes, 50 minutes, 65 minutes & 80 minutes. Throughout the mentioned time frame, group D had faster onset of sedation than Group M. Ramsay’s Sedation score in patients who received Dexmedetomidine was of higher grade than those who received Midazolam. CONCLUSION: Dexmedetomidine had a better satisfactory sedation compared to Midazolam. Midazolam provided a lesser haemodynamic fluctuation compared to Dexmedetomidine throughout the intraoperative period.