A COMPARISON OF SUBLINGUAL WITH VAGINAL ADMINISTRATION OF MISOPROSTOL FOR INDUCTION OF LABOR AT TERM

Dr. Dasharatha Murmu; Dr. K Vandana; Dr. R S Srilakshmi

Volume : VIII, Issue : VI, June - 2018

A COMPARISON OF SUBLINGUAL WITH VAGINAL ADMINISTRATION OF MISOPROSTOL FOR INDUCTION OF LABOR AT TERM

Dr. Dasharatha Murmu, Dr. K Vandana, Dr. R S Srilakshmi

Abstract :

Background: To compare the efficacy and safety of sublingual route of misoprostol with vaginal route of administration.

Methods: This study was conducted at Department of Obstetrics and Gynecology, Alluri Sitarama Raju Academy of Medical Sciences, Eluru, India. 50 cases each with a singleton term pregnancy and a live fetus requiring induction of labor were allocated to sublingual and vaginal administration of misoprostol. Outcome measures related to labor and maternal and fetal side effects were compared between the two groups and evaluated using Chi square test and t–test.

Results: The sublingual route of misoprostol was associated with a reduced risk of failed induction, reduced induction to delivery interval. The incidence of cesarean sections, major side effects and vaginal delivery were similar in both the group. Neonatal outcomes of both groups were comparable.

Conclusions: The sublingual route of administration of misoprostol is comparable in efficacy and safety to the vaginal route for induction.