Volume : VII, Issue : V, May - 2017
A CRITICAL ASSESSMENT OF ADVERSE DRUG REACTIONS DUE TO FIRST LINE ANTI TUBERCULAR DRUGS IN DOTS THERAPY
Dr. Kajal Shilpi, Dr. Lokendra Dave, Dr. A. K. Srivastav
Abstract :
Objective of the study is to assess ADR due to DOTS Therapy. 151 patients suffering with Pulmonary / Extrapulmonary tuberculosis were included in the study. 36 patients developed ADR showing incidence of 23.84%. 15 patients showed more than 1 ADR with total ADR to be 52. ADR in Gastrointestinal System was 42.3% ,Cutaneous system ADR was 19.2 % , musculoskeletal system was 11.5 % ,ototoxocity was 9.6 % , nervous system was 7.6 %, liver and biliary system was 5.7 % and others was 3.8 %. 40. 3% of ADR were due to Isoniazid, 25% because of Rifampin, 17.3% due to Pyrazinamide, 7.6% due to Ethambutol and 9.6% due to Streptomycin . 57.6 % cases were of mild grading in severity and 42.3 % were moderate. 67.3% of the cases had a possible relation with the drug. 32.6% ADR were assessed as probable .
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DOI : 10.36106/ijar
Cite This Article:
Dr. Kajal Shilpi, Dr. Lokendra Dave, Dr. A.K. Srivastav, A CRITICAL ASSESSMENT OF ADVERSE DRUG REACTIONS DUE TO FIRST LINE ANTI TUBERCULAR DRUGS IN DOTS THERAPY, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾5 | May‾2017
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Dr. Kajal Shilpi, Dr. Lokendra Dave, Dr. A.K. Srivastav, A CRITICAL ASSESSMENT OF ADVERSE DRUG REACTIONS DUE TO FIRST LINE ANTI TUBERCULAR DRUGS IN DOTS THERAPY, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾5 | May‾2017
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