Volume : X, Issue : I, January - 2020

A CROSS SECTIONAL STUDY TO ASSESS THE COGNITIVE FUNCTIONS OF PATIENTS ON CHRONIC STATIN THERAPY IN A TERTIARY CARE HOSPITAL

G Santhya, Yamuna Devi

Abstract :

INTRODUCTION: . Statins are drugs which Act by lowering serum cholesterol levels and inhibiting enzymatic reactions that lead to amyloid deposition and plaque formation; both considered cornerstone pathways leading to the development of Alzheimer’s disease. OBJECTIVE:To assess the cognitive functions of patients on chronic statin therapy. MATERIALS AND METHODS:This is a cross–sectional study done at Saveetha Hospital,Chennai. Patients were iefed and a written informed consent was obtained. They were given a Mini Mental State Examination questionnaire and their scores were entered. The data, thus collected was analyzed using SPSS software version 20 CONCLUSION: The study shows that as the duration of statin therapy increases, the risk of cognitive impairments also increase. On analyzing the average Mini Mental State Examination scores, a constant decline of 3.33% was found between the subsequent groups as age increased and a 4% decline as a result of increased duration of statin therapy.

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Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

A CROSS SECTIONAL STUDY TO ASSESS THE COGNITIVE FUNCTIONS OF PATIENTS ON CHRONIC STATIN THERAPY IN A TERTIARY CARE HOSPITAL, G Santhya, Yamuna devi INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-1 | January-2020

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