A histopathological study of association Helicobacter pylori infection with carcinoma stomach in JLNMCH, Bhagalpur

Dr. Ankur; Dr. Mritunjay Kumar

Volume : VII, Issue : VII, July - 2017

A histopathological study of association Helicobacter pylori infection with carcinoma stomach in JLNMCH, Bhagalpur

Dr. Ankur, Dr. Mritunjay Kumar

Abstract :

Aim: The aim of the study is to see the correlation of carcinoma stomach with infection by Helicobacter pylori by means of histopathology. Methods: In this study, 80 malignant looking lesions biopsies were taken by endoscopy. The study was done between April 2016 to March 2017 in department of pathology, JLNMCH, Bhagalpur. Thorough histo pathological analysis were done with H & E stained slides and special stains for the detection on Helicobacter pylori– i.e. Giemsa, Triple stain. Results: The study showed that in 48 biopsies were malignant and 32 biopsies were not associated with malignancies. H. Pylori infection was seen association in 25 cases of malignant biopsies and 14 cases of non malignant biopsies. Males were more affected than females. Average age of presentation of malignancy was 55years. Most common presentation was dysphagia. Most common carcinoma associated with h pylori infection was adenocarcinoma of stomach. Conclusion– It was shown in this study that H.pylori infection is the major risk factor for the development of Gastric carcinoma.