A hospital based study on efficacy of Dexmedetomidine and nalbuphine sedative effects in pediatric dental patients

Shafaat Mohammad; Ausaf Ahmad

Volume : IX, Issue : IV, April - 2019

A hospital based study on efficacy of Dexmedetomidine and nalbuphine sedative effects in pediatric dental patients

Shafaat Mohammad, Ausaf Ahmad

Abstract :

Background and objective: Severe anxiety and extreme fear experienced by younger children regarding dental procedures have made dentists reluctant to render medical care to them. Many dentists prefer to refer young patients to centers capable of offering general anesthesia or conscious sedation. Objective: this study is aimed to compare efficacy of Dexmedetomidine and nalbuphine sedative effects in pediatric dental patients Materials and Methods: Cross sectional study was conducted in Department of Dentistry, Integral institute of medical sciences and research, Lucknow. Forty eight generally healthy children between 4–8 years of age for whom basic behavior modification techniques were not successful in providing dental treatment were considered for the study. Each parent or guardian was requested to fill a written informed consent form at the initial appointment. All the analysis was carried out on SPSS 16.0 in version. Result: Mean value of onset of sedation for atomizer was 13.2±3.7minutes and nasal drop was 11.5±2.3 minutes so atomizer has rapid onset of action. Efficacy parameter for the intranasal dexmedetomidine was found to be the improved for procedural sedation. Intranasal administration with atomizer and nasal drop has no significant difference. Conclusion: Combination of dexmedetomidine and nalbuphine provided a safe and useful sedative alternative for dental treatment in a pediatric patient. Further studies are needed to establish the optimal doses of dexmedetomidine and nalbuphine when used in combination