A Prospective Cross Sectional Study to Evaluate the Relationship between Maximum Standardized Uptake Value of [18f]-Fluoro-2-Deoxy-Glucose PET and Standard Prognostic Markers in Patients with Breast Cancer

Richa Joshi; Ramakrishnan Shankaran

Volume : VIII, Issue : II, February - 2018

A Prospective Cross Sectional Study to Evaluate the Relationship between Maximum Standardized Uptake Value of [18f]-Fluoro-2-Deoxy-Glucose PET and Standard Prognostic Markers in Patients with Breast Cancer

Richa Joshi, Ramakrishnan Shankaran

Abstract :

Background: Studies have demonstrated the prognostic value of FDG Maximum Standardized Uptake (SUV) uptake in various tumours, including head and neck cancer, lung cancer and cervical cancer but the same has not been validated for east cancer. Method: 120 patients with east cancer were evaluated and correlated with FDG PET SUV score and various prognostic markers of tumour size, lymph node status, grade, ER/PR and Her 2 neu status. Results: SUV correlated significantly with histopathological prognostic markers of tumor size, grade and, triple negativity. There was also correlation with ER and PR status though statistical significance was not reached. Conclusion: PET CT has the potential to emerge as a preoperative prognostic marker and can emerge as a useful adjunctive imaging modality to diagnose as well as prognosticate east cancer.