Volume : IX, Issue : III, March - 2019

A prospective randomized comparative double blind study to evaluate the efficacy of dexmedetomidine to bupivacaine given intrathecally as a anaesthetic agents

S. Madankumar, S. Parthibhan

Abstract :

Background: The regional anesthetic technique is the most preferred type of anesthesia in lower abdominal surgeries. The subarachnoid blockade is the commonly used technique for hysterectomy surgery as it is easy to perform, economical and also provides effective sensory and motor blockade. Despite the many advantages of spinal anesthetic, the relatively short duration of the local anesthetic, during prolonged surgery can be a problem. So various adjuvants have been investigated and tried with intrathecal bupivacaine in order to prolong the effects of spinal anesthetic. Materials & Methods: The study done was a prospective, randomized double blind trial in 50 patients undergoing elective hysterectomy under subarachnoid blockade. The patients were randomly allocated in to 2 groups, Group A and Group B by picking random lots from a sealed bag and received the intrathecal drug as per the groups. Motor blockade and the level of sedation was assessed Results: The maximum level of sensory blockade of T4 was achieved in 9 patients in Group A compared to 15 patients in Group B. There was statistically Significant difference between the 2 groups in the maximum level of sensory blockade .The mean time taken for two segment regression of sensory block was 147.36 minutes in Group A. 201.52 minutes in Group B. There was statistically significant difference in 2 segment regression time when Group A is compared to Group B with the P Value < 0.001.Conclusion: It was concluded that supplementation of 10 mcg of dexmedetomidine to 15mg of 0.5% heavy bupivacaine prolonged the duration of analgesia with stable hemodynamics and minimal sedation

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

A PROSPECTIVE RANDOMIZED COMPARATIVE DOUBLE BLIND STUDY TO EVALUATE THE EFFICACY OF DEXMEDETOMIDINE TO BUPIVACAINE GIVEN INTRATHECALLY AS A ANAESTHETIC AGENTS , S. MadanKumar, S. Parthibhan INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-3 | March-2019

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