A Rare Case of Caudal Regression Syndrome : A Case Report

Volume : VIII, Issue : VI, June - 2018

Dr. Venkatesan Sanjeevi, Prof Thiruvalluvan Arumugam

Summary Background: Caudal regression syndrome is a rare, neural tube defect characterized by development of the

caudal aspect of the verteal column and the spinal cord. Although its precise etiology is not known, toxic, ischemic, or

infectious etiologies before the 4th week of gestation are thought to be associated with this syndrome.it results in neurological deficits ranging

from bladder and bowel involvement to severe sensory and motor deficits in the lower limbs.

Case Report: We present a 11 months old female child with caudal regression syndrome, clinical findings are swelling in the lumbosacral region

with bilateral foot deformity and MRI lumbosacral findings are complete sacral agenesis, myeleomeningocele,tethered cord,left renal

agenesis,conus lipoma,hydrosysringomyelia, lipoma of filum terminale, spina bifida and scoliosis. Patient underwent meningomyelocele repair,

lipoma excision and detethering of cord.

Conclusions: Caudal regression syndrome is a rare entity with a known association with maternal diabetes. It is characterized by sacrococcygeal

dysgenesis with an aupt termination of a blunt– ending spinal cord. Ultrasound and fetal MRI can be used to make prenatal diagnosis. Early

detection and prompt treatment is very important to decrease the risk of complications and thus to improve the diagnosis.